This study was investigated the wound healing effect of Anzer origin propolis specimens on rats’ experimental intestinal incisions. Thirty-four male Wistar albino rats have been divided into five groups, weighing 250-300 gr. Water solution of Anzer propolis (PW3 [n=6], PW7 [n=6]) or ethanolic solution of Anzer propolis (PE3 [n=6], PE7 [n=6]) were administered. Control groups (K3 [n=5], K7 [n=5]) received no treatment. The surgical procedure (day 0) consisted of a laparotomy under general anesthesia, during which the colon was incised and repaired with sutures. The Anzer propolis specimen diluted with physiologic saline was administered by gavage (100 mg/kg/day) for 3 and 7 days before and after surgery to PW3 and PW7 groups. Ethanol dissolved Anzer propolis was administered by gavage (100 mg/kg/day) for 3 and 7 days before and after surgery to PE3 and PE7. Experimental animals have been humanly euthanized on the 3rd and 7th days for biochemical and histopathological evaluations. Serum total oxidant status, total antioxidant status, interleukin-1, interleukin-6, tumor necrosis factor-alpha, myeloperoxidase, hydroxyproline and nitric oxide, levels were measured by ELISA. The incision line sampled to evaluate inflammatory cells, fibroblastic activity, neovascularization, and collagen level. The study indicates that the ethanolic Anzer propolis solution's oral administration has a beneficial effect on intestinal wound healing for seven days pre-and postoperatively (PE7).
Anzer Propolis, intestinal incision wound healing, rat, total antioxidant status, total oxidant status
Primary Language | English |
---|---|
Subjects | Veterinary |
Journal Section | Research Article |
Authors |
|
Supporting Institution | AKÜ BAPK |
Project Number | AKÜ BAPK 18.Kariyer.242 |
Publication Date | January 1, 2022 |
Published in Issue | Year 2022Volume: 69 Issue: 1 |
Bibtex | @research article { auvfd834703, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {1300-0861}, eissn = {1308-2817}, address = {}, publisher = {Ankara University}, year = {2022}, volume = {69}, number = {1}, pages = {91 - 97}, doi = {10.33988/auvfd.834703}, title = {Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision}, key = {cite}, author = {Sarıtaş, Zülfükar and Korkmaz, Musa and Demirel, Hasan Hüseyin and Bülbül, Aziz and Sarıtaş, Tuba Berra and Görücü, Fatma and Koç, Yusuf} } |
APA | Sarıtaş, Z. , Korkmaz, M. , Demirel, H. H. , Bülbül, A. , Sarıtaş, T. B. , Görücü, F. & Koç, Y. (2022). Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 69 (1) , 91-97 . DOI: 10.33988/auvfd.834703 |
MLA | Sarıtaş, Z. , Korkmaz, M. , Demirel, H. H. , Bülbül, A. , Sarıtaş, T. B. , Görücü, F. , Koç, Y. "Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 69 (2022 ): 91-97 <http://vetjournal.ankara.edu.tr/en/pub/issue/67711/834703> |
Chicago | Sarıtaş, Z. , Korkmaz, M. , Demirel, H. H. , Bülbül, A. , Sarıtaş, T. B. , Görücü, F. , Koç, Y. "Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision". Ankara Üniversitesi Veteriner Fakültesi Dergisi 69 (2022 ): 91-97 |
RIS | TY - JOUR T1 - Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision AU - ZülfükarSarıtaş, MusaKorkmaz, Hasan HüseyinDemirel, AzizBülbül, Tuba BerraSarıtaş, FatmaGörücü, YusufKoç Y1 - 2022 PY - 2022 N1 - doi: 10.33988/auvfd.834703 DO - 10.33988/auvfd.834703 T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 91 EP - 97 VL - 69 IS - 1 SN - 1300-0861-1308-2817 M3 - doi: 10.33988/auvfd.834703 UR - https://doi.org/10.33988/auvfd.834703 Y2 - 2021 ER - |
EndNote | %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision %A Zülfükar Sarıtaş , Musa Korkmaz , Hasan Hüseyin Demirel , Aziz Bülbül , Tuba Berra Sarıtaş , Fatma Görücü , Yusuf Koç %T Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision %D 2022 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P 1300-0861-1308-2817 %V 69 %N 1 %R doi: 10.33988/auvfd.834703 %U 10.33988/auvfd.834703 |
ISNAD | Sarıtaş, Zülfükar , Korkmaz, Musa , Demirel, Hasan Hüseyin , Bülbül, Aziz , Sarıtaş, Tuba Berra , Görücü, Fatma , Koç, Yusuf . "Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision". Ankara Üniversitesi Veteriner Fakültesi Dergisi 69 / 1 (January 2022): 91-97 . https://doi.org/10.33988/auvfd.834703 |
AMA | Sarıtaş Z. , Korkmaz M. , Demirel H. H. , Bülbül A. , Sarıtaş T. B. , Görücü F. , Koç Y. Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision. Ankara Univ Vet Fak Derg. 2022; 69(1): 91-97. |
Vancouver | Sarıtaş Z. , Korkmaz M. , Demirel H. H. , Bülbül A. , Sarıtaş T. B. , Görücü F. , Koç Y. Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2022; 69(1): 91-97. |
IEEE | Z. Sarıtaş , M. Korkmaz , H. H. Demirel , A. Bülbül , T. B. Sarıtaş , F. Görücü and Y. Koç , "Wound healing effect of Anzer origin propolis specimens on rats’ intestinal incision", Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 69, no. 1, pp. 91-97, Jan. 2022, doi:10.33988/auvfd.834703 |