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First clinical case of leishmaniosis due to Leishmania infantum in a domestic cat from Turkey

Yıl 2020, Cilt: 9 Sayı: 2, 734 - 737, 06.12.2020

Öz

A 12-year-old, female domestic cat was admitted with a history of suffering from pruritic, recurrent crusting-ulcerative skin lesions on the neck for several years. Physical examination revealed lesions with hair loss, mild crusting, and ulcerative plaques on the neck. Two weeks prior to the presentation, an attempt to treat the cat in a private clinic was unsuccessful. Based on history and dermatological signs, leishmaniosis was suspected. No Leishmania amastigotes were found on microscopical examination of the skin, blood, and lymph node smears stained using Giemsa, and serological tests for detecting FeLV and FIV gave negative results. The presumptive diagnosis was confirmed by the detection of L. infantum DNA by C-nPCR in EDTA blood samples. Treatment with enrofloxacin and supporting drugs for two weeks provided complete recovery of skin lesions one month after the treatment, and the direct detection of pathogen DNA was negative. At a yearly follow-up for 3 years, no clinical recurrences were observed. To the authors’ knowledge, this is the first clinical case of L. infantum infection diagnosed in a domestic cat in Turkey.

Teşekkür

We thank to Prof. Dr. Yusuf Ozbel for reviewing the manuscript. This article presented as an oral presentation at the 10th National Veterinary Internal Medicine Congress held in Nevşehir, Turkey during 27 to 30 June 2013. Summary printed in the abstract book of the congress with the title of "First Case of Clinical Feline Leishmaniasis in Turkey".

Kaynakça

  • Baneth, G., & Solano-Gallego, L. (2012). Leishmaniases. In Greene, C.E., (Eds.) Greene’s Infectious Diseases of the Dog and Cat (4th ed.). St Louis: Saunders Elsevier. pp. 734–749.
  • Bianciardi, P., Fasanella, A., Manzillo, V. F., Trotta, T., Pagano, A., Sorino, S., Gradoni, L., & Oliva, G. (2004). The efficacy of enrofloxacin, alone or combined with metronidazole, in the therapy of canine leishmaniasis. Parasitology Research, 93(6), 486-492. https://doi.org/10.1007/s00436-004-1170-0
  • Can, H., Döşkaya, M., Özdemir, H. G., Şahar, E. A., Karakavuk, M., Pektaş, B., Karakuş, M., Töz, S., Caner, A., Döşkaya, A.D. & İz, S. G. (2016). Seroprevalence of Leishmania infection and molecular detection of Leishmania tropica and Leishmania infantum in stray cats of İzmir, Turkey. Experimental parasitology, 167, 109-114. https://doi.org/10.1016/j.exppara.2016.05.011
  • Chatzis, M. K., Andreadou, M., Leontides, L., Kasabalis, D., Mylonakis, M., Koutinas, A. F., Rallis, T., Ikonomopoulos, J., & Saridomichelakis, M. N. (2014). Cytological and molecular detection of Leishmania infantum in different tissues of clinically normal and sick cats. Veterinary Parasitology, 202(3-4), 217-225. https://doi.org/10.1016/j.vetpar.2014.02.044
  • Francino, O., Altet, L., Sanchez-Robert, E., Rodriguez, A., Solano-Gallego, L., Alberola, J., Ferrer, L., Sánchez, A., & Roura, X. (2006). Advantages of real-time PCR assay for diagnosis and monitoring of canine leishmaniosis. Veterinary Parasitology, 137(3-4), 214-221. https://doi.org/10.1016/j.vetpar.2006.01.011
  • Gramiccia, M. (2011). Recent advances in leishmaniosis in pet animals: epidemiology, diagnostics and anti-vectorial prophylaxis. Veterinary Parasitology, 181(1), 23-30. https://doi.org/10.1016/j.vetpar.2011.04.019
  • Hervás, J., De Lara, F. C. M., Sánchez-Isarria, M. A., Pellicer, S., Carrasco, L., Castillo, J. A., & Gómez-Villamandos, J. C. (1999). Two cases of feline visceral and cutaneous leishmaniosis in Spain. Journal of Feline Medicine and Surgery, 1(2), 101-105. https://doi.org/10.1016/s1098-612x(99)90066-9
  • Koutinas, A.F. & Mylonakis, M.E. (2010, April 17-18). Canine leishmaniasis complicated by tick-borne diseases, common in the Mediterranean countries [Conference presentation]. 2nd International Congress on Canine Leishmaniasis, Pisa, Italy.
  • Leiva, M., Lloret, A., Peña, T., & Roura, X. (2005). Therapy of ocular and visceral leishmaniasis in a cat. Veterinary Ophthalmology, 8(1), 71-75. https://doi.org/10.1111/j.1463-5224.2005.00342.x
  • Maia, C., Gomes, J., Cristóvão, J., Nunes, M., Martins, A., Rebêlo, E., & Campino, L. (2010). Feline Leishmania infection in a canine leishmaniasis endemic region, Portugal. Veterinary Parasitology, 174(3-4), 336-340. https://doi.org/10.1016/j.vetpar.2010.08.030
  • Ozon, C., Marty, P., Pratlong, F., Breton, C., Blein, M., Leliévre, A., & Haas, P. (1998). Disseminated feline leishmaniosis due to Leishmania infantum in Southern France. Veterinary Parasitology, 75(2-3), 273-277. https://doi.org/10.1016/s0304-4017(97)00174-x
  • Paşa, S., Vardarlı, A. T., Erol, N., Karakuş, M., Töz, S., Atasoy, A., Balcıoğlu, İ.C., Tuna, G.E., Ermiş, Ö.V., Ertabaklar, H., & Özbel, Y. (2015). Detection of Leishmania major and Leishmania tropica in domestic cats in the Ege Region of Turkey. Veterinary Parasitology, 212(3-4), 389-392. https://doi.org/10.1016/j.vetpar.2015.07.042
  • Pennisi, M.G. (2002). A high prevalence of feline leishmaniasis in southern Italy. In Killick-Kendrick, R., (Eds.) Canine Leishmaniasis: Moving Towards a Solution, Boxmeer, The Netherlands, Intervet International, pp. 39–48.
  • Pennisi, M. G., Cardoso, L., Baneth, G., Bourdeau, P., Koutinas, A., Miró, G., Oliva, G. & Solano-Gallego, L. (2015). LeishVet update and recommendations on feline leishmaniosis. Parasites & Vectors, 8(1), 302. https://doi.org/10.1186/s13071-015-0909-z
  • Pennisi, M. G., Hartmann, K., Lloret, A., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T., Gruffydd-Jones, T., Hosie, M.J. & Lutz, H. (2013). Leishmaniosis in cats: ABCD guidelines on prevention and management. Journal of Feline Medicine and Surgery, 15(7), 638-642. https://doi.org/10.1177/1098612x13489229
  • Poli, A., Abramo, F., Barsotti, P., Leva, S., Gramiccia, M., Ludovisi, A., & Mancianti, F. (2002). Feline leishmaniosis due to Leishmania infantum in Italy. Veterinary Parasitology, 106(3), 181-191. https://doi.org/10.1016/s0304-4017(02)00081-x
  • Sergent, E., Sergent, E. T., Lombard, J., & Quilichini, M. (1912). La leishmaniose à Alger. Infection simultanée d’un enfant, d’un chien et d’un chat dans la même habitation. Le Bulletin de la Société de Pathologie Exotique, 5, 93-98.
  • Simões-Mattos, L., Bevilaqua, C., Mattos, M., Pompeu, M. (2004). Feline leishmaniasis: uncommon or unknown? Revista Portuguesa Ciências Veterinarias, 99: 79-88.
  • Spickler, A.R. (2010). Leishmaniasis (cutaneous and visceral). In Spickler, A.R., (Eds.) Emerging and Exotic Diseases of Animals. Iowa, USA. CFSPH Iowa State University. pp: 205-210.
  • Toz, S.O., Ertabaklar, H., Ozbel, Y., Balcioglu, C.I., Yildizli, N., Alkan, M.Z. (2005). Seroprevalence of Canine Visceral Leishmaniasis in Kusadasi, Turkey. Turkish Journal of Veterinary and Animal Sciences, 29: 23-26. https://journals.tubitak.gov.tr/veterinary/abstract.htm?id=7359
  • Toz, S. O., Culha, G., Zeyrek, F. Y., Ertabaklar, H., Alkan, M. Z., Vardarlı, A. T., Gunduz, C. & Ozbel, Y. (2013). A real-time ITS1-PCR based method in the diagnosis and species identification of Leishmania parasite from human and dog clinical samples in Turkey. PLOS Neglected Tropical Diseases, 7(5), e2205. https://doi.org/10.1371/journal.pntd.0002205
  • van Eys Guillaume, J. J. M., Schoone, G. J., Kroon, N. C., & Ebeling, S. B. (1992). Sequence analysis of small subunit ribosomal RNA genes and its use for detection and identification of Leishmania parasites. Molecular and Biochemical Parasitology, 51(1), 133-142. https://doi.org/10.1016/0166-6851(92)90208-2
Yıl 2020, Cilt: 9 Sayı: 2, 734 - 737, 06.12.2020

Öz

Kaynakça

  • Baneth, G., & Solano-Gallego, L. (2012). Leishmaniases. In Greene, C.E., (Eds.) Greene’s Infectious Diseases of the Dog and Cat (4th ed.). St Louis: Saunders Elsevier. pp. 734–749.
  • Bianciardi, P., Fasanella, A., Manzillo, V. F., Trotta, T., Pagano, A., Sorino, S., Gradoni, L., & Oliva, G. (2004). The efficacy of enrofloxacin, alone or combined with metronidazole, in the therapy of canine leishmaniasis. Parasitology Research, 93(6), 486-492. https://doi.org/10.1007/s00436-004-1170-0
  • Can, H., Döşkaya, M., Özdemir, H. G., Şahar, E. A., Karakavuk, M., Pektaş, B., Karakuş, M., Töz, S., Caner, A., Döşkaya, A.D. & İz, S. G. (2016). Seroprevalence of Leishmania infection and molecular detection of Leishmania tropica and Leishmania infantum in stray cats of İzmir, Turkey. Experimental parasitology, 167, 109-114. https://doi.org/10.1016/j.exppara.2016.05.011
  • Chatzis, M. K., Andreadou, M., Leontides, L., Kasabalis, D., Mylonakis, M., Koutinas, A. F., Rallis, T., Ikonomopoulos, J., & Saridomichelakis, M. N. (2014). Cytological and molecular detection of Leishmania infantum in different tissues of clinically normal and sick cats. Veterinary Parasitology, 202(3-4), 217-225. https://doi.org/10.1016/j.vetpar.2014.02.044
  • Francino, O., Altet, L., Sanchez-Robert, E., Rodriguez, A., Solano-Gallego, L., Alberola, J., Ferrer, L., Sánchez, A., & Roura, X. (2006). Advantages of real-time PCR assay for diagnosis and monitoring of canine leishmaniosis. Veterinary Parasitology, 137(3-4), 214-221. https://doi.org/10.1016/j.vetpar.2006.01.011
  • Gramiccia, M. (2011). Recent advances in leishmaniosis in pet animals: epidemiology, diagnostics and anti-vectorial prophylaxis. Veterinary Parasitology, 181(1), 23-30. https://doi.org/10.1016/j.vetpar.2011.04.019
  • Hervás, J., De Lara, F. C. M., Sánchez-Isarria, M. A., Pellicer, S., Carrasco, L., Castillo, J. A., & Gómez-Villamandos, J. C. (1999). Two cases of feline visceral and cutaneous leishmaniosis in Spain. Journal of Feline Medicine and Surgery, 1(2), 101-105. https://doi.org/10.1016/s1098-612x(99)90066-9
  • Koutinas, A.F. & Mylonakis, M.E. (2010, April 17-18). Canine leishmaniasis complicated by tick-borne diseases, common in the Mediterranean countries [Conference presentation]. 2nd International Congress on Canine Leishmaniasis, Pisa, Italy.
  • Leiva, M., Lloret, A., Peña, T., & Roura, X. (2005). Therapy of ocular and visceral leishmaniasis in a cat. Veterinary Ophthalmology, 8(1), 71-75. https://doi.org/10.1111/j.1463-5224.2005.00342.x
  • Maia, C., Gomes, J., Cristóvão, J., Nunes, M., Martins, A., Rebêlo, E., & Campino, L. (2010). Feline Leishmania infection in a canine leishmaniasis endemic region, Portugal. Veterinary Parasitology, 174(3-4), 336-340. https://doi.org/10.1016/j.vetpar.2010.08.030
  • Ozon, C., Marty, P., Pratlong, F., Breton, C., Blein, M., Leliévre, A., & Haas, P. (1998). Disseminated feline leishmaniosis due to Leishmania infantum in Southern France. Veterinary Parasitology, 75(2-3), 273-277. https://doi.org/10.1016/s0304-4017(97)00174-x
  • Paşa, S., Vardarlı, A. T., Erol, N., Karakuş, M., Töz, S., Atasoy, A., Balcıoğlu, İ.C., Tuna, G.E., Ermiş, Ö.V., Ertabaklar, H., & Özbel, Y. (2015). Detection of Leishmania major and Leishmania tropica in domestic cats in the Ege Region of Turkey. Veterinary Parasitology, 212(3-4), 389-392. https://doi.org/10.1016/j.vetpar.2015.07.042
  • Pennisi, M.G. (2002). A high prevalence of feline leishmaniasis in southern Italy. In Killick-Kendrick, R., (Eds.) Canine Leishmaniasis: Moving Towards a Solution, Boxmeer, The Netherlands, Intervet International, pp. 39–48.
  • Pennisi, M. G., Cardoso, L., Baneth, G., Bourdeau, P., Koutinas, A., Miró, G., Oliva, G. & Solano-Gallego, L. (2015). LeishVet update and recommendations on feline leishmaniosis. Parasites & Vectors, 8(1), 302. https://doi.org/10.1186/s13071-015-0909-z
  • Pennisi, M. G., Hartmann, K., Lloret, A., Addie, D., Belák, S., Boucraut-Baralon, C., Egberink, H., Frymus, T., Gruffydd-Jones, T., Hosie, M.J. & Lutz, H. (2013). Leishmaniosis in cats: ABCD guidelines on prevention and management. Journal of Feline Medicine and Surgery, 15(7), 638-642. https://doi.org/10.1177/1098612x13489229
  • Poli, A., Abramo, F., Barsotti, P., Leva, S., Gramiccia, M., Ludovisi, A., & Mancianti, F. (2002). Feline leishmaniosis due to Leishmania infantum in Italy. Veterinary Parasitology, 106(3), 181-191. https://doi.org/10.1016/s0304-4017(02)00081-x
  • Sergent, E., Sergent, E. T., Lombard, J., & Quilichini, M. (1912). La leishmaniose à Alger. Infection simultanée d’un enfant, d’un chien et d’un chat dans la même habitation. Le Bulletin de la Société de Pathologie Exotique, 5, 93-98.
  • Simões-Mattos, L., Bevilaqua, C., Mattos, M., Pompeu, M. (2004). Feline leishmaniasis: uncommon or unknown? Revista Portuguesa Ciências Veterinarias, 99: 79-88.
  • Spickler, A.R. (2010). Leishmaniasis (cutaneous and visceral). In Spickler, A.R., (Eds.) Emerging and Exotic Diseases of Animals. Iowa, USA. CFSPH Iowa State University. pp: 205-210.
  • Toz, S.O., Ertabaklar, H., Ozbel, Y., Balcioglu, C.I., Yildizli, N., Alkan, M.Z. (2005). Seroprevalence of Canine Visceral Leishmaniasis in Kusadasi, Turkey. Turkish Journal of Veterinary and Animal Sciences, 29: 23-26. https://journals.tubitak.gov.tr/veterinary/abstract.htm?id=7359
  • Toz, S. O., Culha, G., Zeyrek, F. Y., Ertabaklar, H., Alkan, M. Z., Vardarlı, A. T., Gunduz, C. & Ozbel, Y. (2013). A real-time ITS1-PCR based method in the diagnosis and species identification of Leishmania parasite from human and dog clinical samples in Turkey. PLOS Neglected Tropical Diseases, 7(5), e2205. https://doi.org/10.1371/journal.pntd.0002205
  • van Eys Guillaume, J. J. M., Schoone, G. J., Kroon, N. C., & Ebeling, S. B. (1992). Sequence analysis of small subunit ribosomal RNA genes and its use for detection and identification of Leishmania parasites. Molecular and Biochemical Parasitology, 51(1), 133-142. https://doi.org/10.1016/0166-6851(92)90208-2
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Veteriner Bilimleri
Bölüm Case Report
Yazarlar

Mehmet Gültekin 0000-0002-5197-2403

Mehmet Karakuş 0000-0002-9460-1215

Seray Töz Bu kişi benim 0000-0001-5957-8665

Hüseyin Voyvoda Bu kişi benim 0000-0003-4059-0626

Yayımlanma Tarihi 6 Aralık 2020
Gönderilme Tarihi 8 Aralık 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 9 Sayı: 2

Kaynak Göster

APA Gültekin, M., Karakuş, M., Töz, S., Voyvoda, H. (2020). First clinical case of leishmaniosis due to Leishmania infantum in a domestic cat from Turkey. Animal Health Production and Hygiene, 9(2), 734-737.