Öz
Mycobacterial infection in Nile crocodile tissues sent from a private zoo was characterized pathomorphologically and immunohistochemically in this case. Macroscopically, multifocal, greyish-white areas ranging in size from 1 mm to 5 mm were seen in the lung, liver, and spleen. Histologically, a large number of well-demarcated necrotic areas were seen. These areas included nuclei debris locally. Inflammatory cells along with a couple of multinucleated giant cells surrounded the necrotic cores. Numerous acid-fast bacilli were detected by Ziehl-Neelsen staining method. Immunolabelling for both Mycobacterium bovis and anti-BCG antibodies was positive in each tissue.
Anahtar Kelimeler
Immunohistochemistry Mycobacterial infection Mycobacterium Nile crocodile
Teşekkür
This study was presented as an oral presentation at The 6th International Congress on Veterinary and Animal Sciences held online on 02-04 September 2021.
Kaynakça
- Ariel E, Ladds PW, Roberts BL (1997): Mycobacteriosis in young freshwater crocodiles (Crocodylus johnstoni). Aust Vet J, 75, 831-833.
- Buenviaje GN, Ladds PW, Martin Y (1998): Pathology of skin diseases in crocodiles. Aust Vet J, 76, 357-363.
- Gcebe N, Michel AL, Hlokwe TM (2018): Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa. BMC Microbiol, 18, 32.
- Griffith AS (1928): Tuberculosis in Captive Wild Animals. J Hyg (Lond), 28, 198-218.
- Huchzermeyer FW (2003): Crocodiles: biology, husbandry and diseases. CABI Pub, Wallingford, Oxon, UK.
- Huchzermeyer FW, Huchzermeyer HF (2000): Mycobacterial infections in farmed and captive crocodiles. 109-112. In: Crocodiles. Proceedings of the 15th Working Meeting of the Crocodile Specialist Group. IUCN –The World Conservation Union, Gland, Switzerland.
- Kik MJ (2013): Disseminated Mycobacterium intracellulare infection in a broad-snouted caiman Caiman latirostris. Dis Aquat Organ, 107, 83-86.
- Lécu A, Ball R (2011): Mycobacterial infections in zoo animals: relevance, diagnosis and management. Int Zoo Yearb, 45, 183-202.
- Luna LG (1968). Manual of histologic staining methods of the Armed Forces Institute of Pathology, 3rd ed. Blakiston Division, McGraw-Hill, New York.
- Roh YS, Park H, Cho A, et al (2010): Granulomatous pneumonia in a captive freshwater crocodile (Crocodylus johnstoni) caused by Mycobacterium szulgai. J Zoo Wildl Med, 41, 550-554.
- Shah KK, Pritt BS, Alexander MP (2017): Histopathologic review of granulomatous inflammation. J Clin Tuberc Other Mycobact Dis, 7, 1-12.
- Slany M, Knotek Z, Skoric M, et al (2010): Systemic mixed infection in a brown caiman (Caiman crocodilus fuscus) caused by Mycobacterium szulgai and M. chelonae: a case report. Vet Med-Czech, 55, 91–96.
- Soldati G, Lu ZH, Vaughan L, et al (2004): Detection of mycobacteria and chlamydiae in granulomatous inflammation of reptiles: a retrospective study. Vet Pathol, 41, 388-397.
- Stacy BA, Pessier AP (2007): Host Response to infectious agents and identification of pathogens in tissue section. 257-297. In: ER Jacobson (Ed), Infectious Diseases and Pathology of Reptiles: Color Atlas and Text. CRC Press, Boca Raton, Florida.
- Vural SA, Alçığır ME (2010): Detection of pathomorphological and immunohistochemical findings of tuberculosis in cattle slaughtered in Ankara and its surroundings. Ankara Univ Vet Fak Derg, 57, 253-257.
- Zwart P (1964): Studies on Renal Pathology in Reptiles. Pathol Vet, 1, 542-556.
Öz
Kaynakça
- Ariel E, Ladds PW, Roberts BL (1997): Mycobacteriosis in young freshwater crocodiles (Crocodylus johnstoni). Aust Vet J, 75, 831-833.
- Buenviaje GN, Ladds PW, Martin Y (1998): Pathology of skin diseases in crocodiles. Aust Vet J, 76, 357-363.
- Gcebe N, Michel AL, Hlokwe TM (2018): Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa. BMC Microbiol, 18, 32.
- Griffith AS (1928): Tuberculosis in Captive Wild Animals. J Hyg (Lond), 28, 198-218.
- Huchzermeyer FW (2003): Crocodiles: biology, husbandry and diseases. CABI Pub, Wallingford, Oxon, UK.
- Huchzermeyer FW, Huchzermeyer HF (2000): Mycobacterial infections in farmed and captive crocodiles. 109-112. In: Crocodiles. Proceedings of the 15th Working Meeting of the Crocodile Specialist Group. IUCN –The World Conservation Union, Gland, Switzerland.
- Kik MJ (2013): Disseminated Mycobacterium intracellulare infection in a broad-snouted caiman Caiman latirostris. Dis Aquat Organ, 107, 83-86.
- Lécu A, Ball R (2011): Mycobacterial infections in zoo animals: relevance, diagnosis and management. Int Zoo Yearb, 45, 183-202.
- Luna LG (1968). Manual of histologic staining methods of the Armed Forces Institute of Pathology, 3rd ed. Blakiston Division, McGraw-Hill, New York.
- Roh YS, Park H, Cho A, et al (2010): Granulomatous pneumonia in a captive freshwater crocodile (Crocodylus johnstoni) caused by Mycobacterium szulgai. J Zoo Wildl Med, 41, 550-554.
- Shah KK, Pritt BS, Alexander MP (2017): Histopathologic review of granulomatous inflammation. J Clin Tuberc Other Mycobact Dis, 7, 1-12.
- Slany M, Knotek Z, Skoric M, et al (2010): Systemic mixed infection in a brown caiman (Caiman crocodilus fuscus) caused by Mycobacterium szulgai and M. chelonae: a case report. Vet Med-Czech, 55, 91–96.
- Soldati G, Lu ZH, Vaughan L, et al (2004): Detection of mycobacteria and chlamydiae in granulomatous inflammation of reptiles: a retrospective study. Vet Pathol, 41, 388-397.
- Stacy BA, Pessier AP (2007): Host Response to infectious agents and identification of pathogens in tissue section. 257-297. In: ER Jacobson (Ed), Infectious Diseases and Pathology of Reptiles: Color Atlas and Text. CRC Press, Boca Raton, Florida.
- Vural SA, Alçığır ME (2010): Detection of pathomorphological and immunohistochemical findings of tuberculosis in cattle slaughtered in Ankara and its surroundings. Ankara Univ Vet Fak Derg, 57, 253-257.
- Zwart P (1964): Studies on Renal Pathology in Reptiles. Pathol Vet, 1, 542-556.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Veteriner Patoloji |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Erken Görünüm Tarihi | 21 Eylül 2023 |
| Yayımlanma Tarihi | 1 Nisan 2024 |
| Yayımlandığı Sayı | Yıl 2024 |