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Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits

Yıl 2011, Cilt: 58 Sayı: 4, 261 - 266, 01.12.2011
https://doi.org/10.1501/Vetfak_0000002485

Öz

Effects of intraocular lens (IOL) and\or capsullar tension ring (CTR) usage in prevention of posterior capsullar opasification (PCO) formation in rabbits were studied with ophthalmascopic and histopathologic parameters. Lensectomy by phacoemulsification tecnique in 60 eyes of 30 healthy New Zealand rabbits were made. 30 rabbits were divided into 3 groups. In first group (n=10) IOL is placed after lensectomy, in second group (n=10) CTR and in third group (n=10) IOL+CTR is placed in the right eyes after lensectomy. Ophthalmascopic examinations were made in postoperative period and at the end of the 6 months the rabbits are evaluated with histopathology. In histopathologic examination fibrocyte and fibroblast migration and lens epithelium cell proliferations which are signs of the PCO is less commonly seen in CTR\IOL group. After lensectomy with phacoemulsification long term effects of CTR and\or IOL in prevention of PCO was investigated. In conclusion CTR\IOL group was found to be succesfull in prevention of PCO formation

Kaynakça

  • Dziezyc J (1990): Cataract surgery. Vet Clin North Am Small Anim Pract, 20, 737–753.
  • Gayton JL, Apple DJ, Peng Q, Visessook N, Sanders V, Werner L, Pandey SK, Escobar-Gomez M, Hoddinott DS, Van Der Karr M (2000): Interlenticular opasification: clinicopathological correlation of complication of posterior chamber piggy back intraocular lenses. J Cat Ref Surg, 26, 330-336.
  • Gilger BC (2003): Lens. 1402-1418. In: D Slatter (Ed), Textbook of Small Animal Surgery. Philadelphia Sounders.
  • Kim JH, Kim H, Joo CK (2005): The effect of capsular tension ring on posterior capsular opacity in cataract surgery. Korean J Ophthalmol, 19, 23-28.
  • Kurosaka D, Kato K, Nagamato T (1996): Presence of α smooth muscle actin in lens epithelial cells of aphakic rabbit eyes. Br J Opthalmol, 80, 906-910.
  • Lanzetta P, Chiodini RG, Polito A, Bandello F (2002): Use of capsular tension ring phacoemulsification. Indications and technique. Indian J Ophthalmol, 50, 333-337.
  • Lois N, Dawson R, McKinnon AD, Forrester JV (2004): A New Model of Posterior Capsule Opacification in Rodents. Invest Ophthalmol Vis Sci, 44, 3450-3457.
  • Mc Donell PJ, Stark WJ, Green WR (1984): Posterior capsule opacification: a specular microscopic study. Ophthalmology, 91, 853-856.
  • Nagamoto T, Eguchi G (1997): Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule. Cat Ref Surg, 23, 866-872.
  • Özgencil FE (2003): The results of phacofragmentation and aspiration surgery for cataract extraction in dogs. Turk J Vet Anim Sci, 29,165-173.
  • Pandey SK, Apple DJ, Werner L, Maloof AJ, Milverton EJ (2004): Posterior capsule opacification: A review of the aetiopathogenesis, experimental and clinical studies and factors for prevention. Indian J Ophtalmol, 52, 99–112.
  • Pandey SK, Cochener B, Apple DJ, Colin J, Werner L, Bougaran R, Trivedi RH, Macky TA, İzak AM (2002): Intracapsular ring sustained 5 fluorouracil delivery system for the prevention of posterior capsule opacification in rabbits: a histological study. J Cataract Refr Surg, 28, 139–148.
  • Raj SM, Vasavada AR, Johar K, Vasavada V (2007): Post-operative capsular opacification: a review. International Journal of Biomedical Science, 3, 237–250.
  • Ridley H (1976): The origin and objectives of intraocular lenticular implants. Trans Am Acad Opthalmol Otolaryngol, 81, 65–66.
  • Wormstone IM (2002): Posterior capsule opacification: a cell biological perspective. Exp Eye Res, 74, 337.

Tavşanlarda kapsül germe halkası (KGH)’nın ve/veya intraokuler lens (İOL)’in posterior kapsüller opasifikasyona (PKO) etkisinin değerlendirilmesi

Yıl 2011, Cilt: 58 Sayı: 4, 261 - 266, 01.12.2011
https://doi.org/10.1501/Vetfak_0000002485

Öz

Tavşanlarda intraokuler lens (İOL) ve / veya kapsül germe halkalarının (KGH), posterior kapsüller opasifikasyona (PKO) olan etkisinin oftalmaskopik ve histopatolojik parametreler ile araştırılması amaçlandı. Çalışmada 30 adet sağlıklı ergin Yeni Zelanda tavşanının 60 gözüne fakoemülsifikasyon tekniği ile lensektomi uygulandı. Birinci grubun sağ gözüne (n=10) lensektomi sonrası İOL, ikinci grup sağ gözüne (n=10) lensektomi sonrası KGH, üçüncü grupta yine sağ gözlerine (n=10) lensektomi sonrası İOL ve KGH uygulamaları yapıldı. Deneklerin postoperatif dönemde oftalmaskopik muayeneleri yapıldı ve 6 aylık gözlem süresinin sonunda histopatolojik değerlendirmeye alındı. Histopatolojik değerlendirmede PKO’nun göstergesi olan fibrosit ve fibroblast migrasyonu ve lens epitelyum hücrelerinde proliferasyon açısından KGH\İOL grubunun daha üstün olduğu izlendi. Fakoemülsifikasyon tekniği ile lensektomi sonrası PKO’nun engellenmesinde KGH ve /veya İOL lerin uzun dönem etkisi araştırıldı. Sonuçta KGH\IOL birlikte kullanıldığı gruplarda PKO’nun engellendiği ve bu yöntemin daha başarılı olduğu kanısına varıldı

Kaynakça

  • Dziezyc J (1990): Cataract surgery. Vet Clin North Am Small Anim Pract, 20, 737–753.
  • Gayton JL, Apple DJ, Peng Q, Visessook N, Sanders V, Werner L, Pandey SK, Escobar-Gomez M, Hoddinott DS, Van Der Karr M (2000): Interlenticular opasification: clinicopathological correlation of complication of posterior chamber piggy back intraocular lenses. J Cat Ref Surg, 26, 330-336.
  • Gilger BC (2003): Lens. 1402-1418. In: D Slatter (Ed), Textbook of Small Animal Surgery. Philadelphia Sounders.
  • Kim JH, Kim H, Joo CK (2005): The effect of capsular tension ring on posterior capsular opacity in cataract surgery. Korean J Ophthalmol, 19, 23-28.
  • Kurosaka D, Kato K, Nagamato T (1996): Presence of α smooth muscle actin in lens epithelial cells of aphakic rabbit eyes. Br J Opthalmol, 80, 906-910.
  • Lanzetta P, Chiodini RG, Polito A, Bandello F (2002): Use of capsular tension ring phacoemulsification. Indications and technique. Indian J Ophthalmol, 50, 333-337.
  • Lois N, Dawson R, McKinnon AD, Forrester JV (2004): A New Model of Posterior Capsule Opacification in Rodents. Invest Ophthalmol Vis Sci, 44, 3450-3457.
  • Mc Donell PJ, Stark WJ, Green WR (1984): Posterior capsule opacification: a specular microscopic study. Ophthalmology, 91, 853-856.
  • Nagamoto T, Eguchi G (1997): Effect of intraocular lens design on migration of lens epithelial cells onto the posterior capsule. Cat Ref Surg, 23, 866-872.
  • Özgencil FE (2003): The results of phacofragmentation and aspiration surgery for cataract extraction in dogs. Turk J Vet Anim Sci, 29,165-173.
  • Pandey SK, Apple DJ, Werner L, Maloof AJ, Milverton EJ (2004): Posterior capsule opacification: A review of the aetiopathogenesis, experimental and clinical studies and factors for prevention. Indian J Ophtalmol, 52, 99–112.
  • Pandey SK, Cochener B, Apple DJ, Colin J, Werner L, Bougaran R, Trivedi RH, Macky TA, İzak AM (2002): Intracapsular ring sustained 5 fluorouracil delivery system for the prevention of posterior capsule opacification in rabbits: a histological study. J Cataract Refr Surg, 28, 139–148.
  • Raj SM, Vasavada AR, Johar K, Vasavada V (2007): Post-operative capsular opacification: a review. International Journal of Biomedical Science, 3, 237–250.
  • Ridley H (1976): The origin and objectives of intraocular lenticular implants. Trans Am Acad Opthalmol Otolaryngol, 81, 65–66.
  • Wormstone IM (2002): Posterior capsule opacification: a cell biological perspective. Exp Eye Res, 74, 337.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Veteriner Cerrahi
Diğer ID JA85RF38FY
Bölüm Araştırma Makalesi
Yazarlar

Rıfkı Hazıroğlu

İrem Gül Sancak

Fatih Karel

Mehmet Eray Alçığır

Nilüfer Yalçındağ

Oytun Okan Şenel

Bülent Fahri İnce

Fatma Eser Özgencil

Yayımlanma Tarihi 1 Aralık 2011
Yayımlandığı Sayı Yıl 2011Cilt: 58 Sayı: 4

Kaynak Göster

APA Hazıroğlu, R., Sancak, İ. G., Karel, F., Alçığır, M. E., vd. (2011). Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 58(4), 261-266. https://doi.org/10.1501/Vetfak_0000002485
AMA Hazıroğlu R, Sancak İG, Karel F, Alçığır ME, Yalçındağ N, Şenel OO, İnce BF, Özgencil FE. Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits. Ankara Univ Vet Fak Derg. Aralık 2011;58(4):261-266. doi:10.1501/Vetfak_0000002485
Chicago Hazıroğlu, Rıfkı, İrem Gül Sancak, Fatih Karel, Mehmet Eray Alçığır, Nilüfer Yalçındağ, Oytun Okan Şenel, Bülent Fahri İnce, ve Fatma Eser Özgencil. “Investigation of the Effects of IOL and/Or Capsullar Tension Ring (CTR) on Posterior Capsullaropasification (PCO) Development in Rabbits”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 58, sy. 4 (Aralık 2011): 261-66. https://doi.org/10.1501/Vetfak_0000002485.
EndNote Hazıroğlu R, Sancak İG, Karel F, Alçığır ME, Yalçındağ N, Şenel OO, İnce BF, Özgencil FE (01 Aralık 2011) Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits. Ankara Üniversitesi Veteriner Fakültesi Dergisi 58 4 261–266.
IEEE R. Hazıroğlu, İ. G. Sancak, F. Karel, M. E. Alçığır, N. Yalçındağ, O. O. Şenel, B. F. İnce, ve F. E. Özgencil, “Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits”, Ankara Univ Vet Fak Derg, c. 58, sy. 4, ss. 261–266, 2011, doi: 10.1501/Vetfak_0000002485.
ISNAD Hazıroğlu, Rıfkı vd. “Investigation of the Effects of IOL and/Or Capsullar Tension Ring (CTR) on Posterior Capsullaropasification (PCO) Development in Rabbits”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 58/4 (Aralık 2011), 261-266. https://doi.org/10.1501/Vetfak_0000002485.
JAMA Hazıroğlu R, Sancak İG, Karel F, Alçığır ME, Yalçındağ N, Şenel OO, İnce BF, Özgencil FE. Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits. Ankara Univ Vet Fak Derg. 2011;58:261–266.
MLA Hazıroğlu, Rıfkı vd. “Investigation of the Effects of IOL and/Or Capsullar Tension Ring (CTR) on Posterior Capsullaropasification (PCO) Development in Rabbits”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 58, sy. 4, 2011, ss. 261-6, doi:10.1501/Vetfak_0000002485.
Vancouver Hazıroğlu R, Sancak İG, Karel F, Alçığır ME, Yalçındağ N, Şenel OO, İnce BF, Özgencil FE. Investigation of the effects of IOL and/or capsullar tension ring (CTR) on posterior capsullaropasification (PCO) development in rabbits. Ankara Univ Vet Fak Derg. 2011;58(4):261-6.