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The investigation of the plasma monocyte chemoattractant protein-1 and interleukin-1α levels and the relationship between these levels and number of blood lymphocytes and monocytes in calves with foot and mouth disease

Yıl 2006, Cilt: 53 Sayı: 2, 91 - 95, 01.06.2006

Fatma Gül Yarım Cevat Nisbet Naci Öcal Gülay Çiftçi Aydın Coşkuner

https://doi.org/10.1501/Vetfak_0000000079

Öz

: In this study, detection of plasma monocyte chemoattractant protein-1 (MCP-1) and interleukin-1 (IL-1α) levels
and correlations between these levels and blood lymphocyte and monocyte numbers was aimed. 1-1.5 years old 16 calves with foot
and mouth disease and 11 calves with healthy were used in study. The levels of MCP-1 and IL-1α in plasma were found to be
significantly increased in calves with foot and mouth disease compared to healthy group (p<0.001). Between the plasma MCP-1 and
IL-1α levels and blood lymphocyte and monocyte numbers were determined to be significantly correlated (p<0.01) in calves with
foot and mouth disease. In the present study, the number of blood lymphocytes and monocytes was positively correlated with plasma
MCP-1 and IL-1α concentrations that suggests MCP-1 and IL-1α are involved in etiopathogenesis of foot and mouth disease

Anahtar Kelimeler

Calf foot and mouth disease IL-1α lymphocyte MCP-1 monocyte

Kaynakça

  • Aderka D, Holtmann H, Toker L, Hahn T, Wallach D (1986): Tumor necrosis factor induction by Sendai virus. J Immunol, 136, 2938-2342.
  • Apte RN, Voronov E (2002): Interleukin-1--a major pleiotropic cytokine in tumor-host interactions. Semin Cancer Biol, 12, 277-290.
  • Baggiolini M, Dewald B, Moser B (1997): Human chemokines: an update. Annu Rev Immunol, 15, 675-705.
  • Boring L, Gosling J, Cleary M, Charo IF (1998): Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature, 394, 894– 897.
  • Breen EC, Rezai K, Nakajima K, Beall GN, Mitsuyasu RT, Hirano T, Kishimoto T, Martinez-Maza O (1990): Infection with HIV is associated with elevated IL-6 levels and production. J Immunol, 144, 480-484.
  • Bubfeld D, Kaufmann A, Meyer RG, Gemsa D, Sprenger H (1998): Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated ınfluenza A virus. Cell Immun, 186, 1-7.
  • Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM (1990): Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA, 87, 5134-5138.
  • Davies C (1994): Principles. In The Immunoassay Handbook. D. Wild, ed. Stockton Press, New York, p. 3- 47.
  • Dinarello CA (1996): Biologic basis for interleukin-1 in disease. Blood, 87, 2095-2147.
  • Dinter Z, Morein B (1990): Virus Infections of Ruminants, Elsevier Science Publishers B.V. p. 506-508.
  • Dunphy J, Horvath A, Barcham G, Balic A, Bischof R, Meeusen E (2001): Isolation, characterisation and expression of mRNAs encoding the ovine CC chemokines, monocyte chemoattractant protein (MCP)-1alpha and -2. Vet Immunol Immunopathol, 82, 153-164.
  • Eckersall PD (2000): Recent advances and future pros- pects for the use of acute phase proteins as markers of dis- ease in animals. Revue Med Vet, 151, 577-584.
  • England JM, Rowan RM, van Assendelft OW, Coulter WH, Groner W, Jones AR, Koepke JA, Lewis SM, Shinton NK, Thom R (1984): Protocol for evaluation of automated blood cell counters. International Committee for Standardization in Haematology (ICSH). Clin Lab Haematol, 6, 269-84.
  • Gangur V, Birmingham NP, Thanesvorakul S (2002): Chemokines in health and disease. Vet Immunol Immunopathol, 86, 127-136.
  • Gu L, Tseng S, Rollins BJ (1999): Monocyte chemoattractant protein-1. Chem Immunol, 72, 7– 29.
  • Horadagoda NU, Knox KM, Gibbs HA, Reid SW, Horadagoda A, Edwards SE, Eckersall PD (1999): Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Vet Rec, 17, 144, 437- 441.
  • Imhof BA, Dunon D (1995): Leukocyte migration and adhesion. Adv Immunol, 58, 345-416.
  • Janeway CA, Medzhitov R (2002): Innate immune rec- ognition. Annu Rev Immunol, 20, 197-216.
  • Kuby J (1997): Immunology, 3rd Ed., WH Freeman and Co, New York.
  • Lechner F, Machado J, Bertoni G, Seow HF, Dobbelaere DA, Peterhans E (1997): Caprine arthritis encephalitis virus dysregulates the expression of cytokines in macrophages. J Virol, 71, 7488-7497.
  • Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ (1998): Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1- deficient mice. J Exp Med, 187, 601-608.
  • Luster AD (1998): Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med, 338, 436-445.
  • Mackay CR (2001): Chemokines: immunology's high impact factors. Nat Immunol, 2, 95-101.
  • Mahad DJ, Ransohoff RM (2003): The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol, 15, 23– 32.
  • Mc Cullough, KC, Crowther, JR (1986): The protective immune response against foot and mouth disease virus, re- lationship to virion topography. FMD Bulletin, 23, 2-6.
  • Rao CR (1973): Linear statistical inference and its appli- cations. John&Sons, New York.
  • Reckless J, Rubin EM, Verstuyft JB, Metcalfe JC, Grainger DJ (1999): Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. Circulation, 99, 2310-2306.
  • Sallusto F, Lanzavecchia A, Mackay CR (1998): Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today, 19, 568-574.
  • Sorbino F, Saiz M, Jimenez-Clavero MA, Nunez JI, Rosas MF, Baranowski E, Ley V (2001): Foot and Mouth Disease Virus: a long known virus, but a current threat. Vet Res, 32, 1-30.
  • Thanawongnuwech R, Young TF, Thacker BJ, Thacker EL (2001): Differential production of proinflammatory cytokines: in vitro PRRSV and Mycoplasma hyopneumoniae co-infection model. Vet Immunol Immunopathol, 79, 115-127.
  • Usherwood EJ, Nash AA (1995): Lymphocyte recognition of picornaviruses. J Gen Virol, 76, 499-508.
  • Van Reeth, Labarque G, Nauwynck H, Pensaert M (1999): Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: correlations with pathogenicity. Res Vet Sci, 67, 47-52.
  • Van Reeth K, Van Gucht S, Pensaert M (2002): In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome bu rewarding. Vet Immunol Immunopathol, 87, 161-168.
  • Wong CK, Lam CW, Wu AK, Ip WK, Lee NL, Chan IH, Lit LC, Hui DS, Chan MH, Chung SS, Sung JJ (2004): Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol, 136, 95-103.
  • Yadav S, Sharma R, Chhabra R (2005): Interleukin-2 potentiates foot-and-mouth disease vaccinal immune responses in mice. Vaccine, 23, 3005-3009.
  • Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ (1989): Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med, 169, 1449-1459.
  • Zoja C, Wang JM, Bettoni S, Sironi M, Renzi D, Chiaffarino F, Abboud HE, Van Damme J, Mantovani A, Remuzzi G (1991): Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony- stimulating factors, and interleukin-6 in human mesengial cells. Am J Pathol, 138, 991-1003.

Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi

Yıl 2006, Cilt: 53 Sayı: 2, 91 - 95, 01.06.2006

Fatma Gül Yarım Cevat Nisbet Naci Öcal Gülay Çiftçi Aydın Coşkuner

https://doi.org/10.1501/Vetfak_0000000079

Öz

Bu çalışmada, şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 (MCP-1) ve interlökin 1-α (IL-1α) düzeylerinin ve bu düzeyler ile kandaki lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi amaçlandı. Bu amaçla, 1-1.5
yaşlarında 16 adet şap hastalıklı ve 11 adet sağlıklı dana kullanıldı. Şap hastalıklı danalarda plazma MCP-1 ve IL-1α düzeyleri sağlıklı gruba göre önemli derecede yükselmiş bulundu (p<0.001). Şap hastalıklı danalarda plazma MCP-1 ve IL-1α düzeyleri ile kandaki lenfosit ve monosit sayıları arasında önemli derecede ilişki olduğu belirlendi (p<0.01). Kandaki lenfosit ve monosit artışına
paralel olarak plazma MCP-1 ve IL1-α düzeylerinin de önemli derecede artmış olması, MCP-1 ve IL-1α’nın şap hastalığının
patogenezinde rol aldığını düşündürmektedir

Anahtar Kelimeler

Dana IL-1α lenfosit MCP-1 monosit şap hastalığı

Kaynakça

  • Aderka D, Holtmann H, Toker L, Hahn T, Wallach D (1986): Tumor necrosis factor induction by Sendai virus. J Immunol, 136, 2938-2342.
  • Apte RN, Voronov E (2002): Interleukin-1--a major pleiotropic cytokine in tumor-host interactions. Semin Cancer Biol, 12, 277-290.
  • Baggiolini M, Dewald B, Moser B (1997): Human chemokines: an update. Annu Rev Immunol, 15, 675-705.
  • Boring L, Gosling J, Cleary M, Charo IF (1998): Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature, 394, 894– 897.
  • Breen EC, Rezai K, Nakajima K, Beall GN, Mitsuyasu RT, Hirano T, Kishimoto T, Martinez-Maza O (1990): Infection with HIV is associated with elevated IL-6 levels and production. J Immunol, 144, 480-484.
  • Bubfeld D, Kaufmann A, Meyer RG, Gemsa D, Sprenger H (1998): Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated ınfluenza A virus. Cell Immun, 186, 1-7.
  • Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM (1990): Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA, 87, 5134-5138.
  • Davies C (1994): Principles. In The Immunoassay Handbook. D. Wild, ed. Stockton Press, New York, p. 3- 47.
  • Dinarello CA (1996): Biologic basis for interleukin-1 in disease. Blood, 87, 2095-2147.
  • Dinter Z, Morein B (1990): Virus Infections of Ruminants, Elsevier Science Publishers B.V. p. 506-508.
  • Dunphy J, Horvath A, Barcham G, Balic A, Bischof R, Meeusen E (2001): Isolation, characterisation and expression of mRNAs encoding the ovine CC chemokines, monocyte chemoattractant protein (MCP)-1alpha and -2. Vet Immunol Immunopathol, 82, 153-164.
  • Eckersall PD (2000): Recent advances and future pros- pects for the use of acute phase proteins as markers of dis- ease in animals. Revue Med Vet, 151, 577-584.
  • England JM, Rowan RM, van Assendelft OW, Coulter WH, Groner W, Jones AR, Koepke JA, Lewis SM, Shinton NK, Thom R (1984): Protocol for evaluation of automated blood cell counters. International Committee for Standardization in Haematology (ICSH). Clin Lab Haematol, 6, 269-84.
  • Gangur V, Birmingham NP, Thanesvorakul S (2002): Chemokines in health and disease. Vet Immunol Immunopathol, 86, 127-136.
  • Gu L, Tseng S, Rollins BJ (1999): Monocyte chemoattractant protein-1. Chem Immunol, 72, 7– 29.
  • Horadagoda NU, Knox KM, Gibbs HA, Reid SW, Horadagoda A, Edwards SE, Eckersall PD (1999): Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Vet Rec, 17, 144, 437- 441.
  • Imhof BA, Dunon D (1995): Leukocyte migration and adhesion. Adv Immunol, 58, 345-416.
  • Janeway CA, Medzhitov R (2002): Innate immune rec- ognition. Annu Rev Immunol, 20, 197-216.
  • Kuby J (1997): Immunology, 3rd Ed., WH Freeman and Co, New York.
  • Lechner F, Machado J, Bertoni G, Seow HF, Dobbelaere DA, Peterhans E (1997): Caprine arthritis encephalitis virus dysregulates the expression of cytokines in macrophages. J Virol, 71, 7488-7497.
  • Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, North R, Gerard C, Rollins BJ (1998): Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1- deficient mice. J Exp Med, 187, 601-608.
  • Luster AD (1998): Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med, 338, 436-445.
  • Mackay CR (2001): Chemokines: immunology's high impact factors. Nat Immunol, 2, 95-101.
  • Mahad DJ, Ransohoff RM (2003): The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol, 15, 23– 32.
  • Mc Cullough, KC, Crowther, JR (1986): The protective immune response against foot and mouth disease virus, re- lationship to virion topography. FMD Bulletin, 23, 2-6.
  • Rao CR (1973): Linear statistical inference and its appli- cations. John&Sons, New York.
  • Reckless J, Rubin EM, Verstuyft JB, Metcalfe JC, Grainger DJ (1999): Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. Circulation, 99, 2310-2306.
  • Sallusto F, Lanzavecchia A, Mackay CR (1998): Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today, 19, 568-574.
  • Sorbino F, Saiz M, Jimenez-Clavero MA, Nunez JI, Rosas MF, Baranowski E, Ley V (2001): Foot and Mouth Disease Virus: a long known virus, but a current threat. Vet Res, 32, 1-30.
  • Thanawongnuwech R, Young TF, Thacker BJ, Thacker EL (2001): Differential production of proinflammatory cytokines: in vitro PRRSV and Mycoplasma hyopneumoniae co-infection model. Vet Immunol Immunopathol, 79, 115-127.
  • Usherwood EJ, Nash AA (1995): Lymphocyte recognition of picornaviruses. J Gen Virol, 76, 499-508.
  • Van Reeth, Labarque G, Nauwynck H, Pensaert M (1999): Differential production of proinflammatory cytokines in the pig lung during different respiratory virus infections: correlations with pathogenicity. Res Vet Sci, 67, 47-52.
  • Van Reeth K, Van Gucht S, Pensaert M (2002): In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome bu rewarding. Vet Immunol Immunopathol, 87, 161-168.
  • Wong CK, Lam CW, Wu AK, Ip WK, Lee NL, Chan IH, Lit LC, Hui DS, Chan MH, Chung SS, Sung JJ (2004): Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol, 136, 95-103.
  • Yadav S, Sharma R, Chhabra R (2005): Interleukin-2 potentiates foot-and-mouth disease vaccinal immune responses in mice. Vaccine, 23, 3005-3009.
  • Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ (1989): Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med, 169, 1449-1459.
  • Zoja C, Wang JM, Bettoni S, Sironi M, Renzi D, Chiaffarino F, Abboud HE, Van Damme J, Mantovani A, Remuzzi G (1991): Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony- stimulating factors, and interleukin-6 in human mesengial cells. Am J Pathol, 138, 991-1003.
Toplam 37 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Cerrahi
Bölüm Araştırma Makalesi
Yazarlar

Fatma Gül Yarım

Cevat Nisbet

Naci Öcal

Gülay Çiftçi

Aydın Coşkuner

Yayımlanma Tarihi 1 Haziran 2006
Yayımlandığı Sayı Yıl 2006Cilt: 53 Sayı: 2

Kaynak Göster

APA Yarım, F. G., Nisbet, C., Öcal, N., Çiftçi, G., vd. (2006). Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 53(2), 91-95. https://doi.org/10.1501/Vetfak_0000000079
AMA Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A. Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Univ Vet Fak Derg. Haziran 2006;53(2):91-95. doi:10.1501/Vetfak_0000000079
Chicago Yarım, Fatma Gül, Cevat Nisbet, Naci Öcal, Gülay Çiftçi, ve Aydın Coşkuner. “Şap hastalıklı Danalarda Plazma Monosit Kemoatraktan Protein-1 Ve İnterlökin-1α düzeylerinin Ve Bu düzeylerle Kan Lenfosit Ve Monosit sayıları arasındaki ilişkilerin Incelenmesi”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 53, sy. 2 (Haziran 2006): 91-95. https://doi.org/10.1501/Vetfak_0000000079.
EndNote Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A (01 Haziran 2006) Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Üniversitesi Veteriner Fakültesi Dergisi 53 2 91–95.
IEEE F. G. Yarım, C. Nisbet, N. Öcal, G. Çiftçi, ve A. Coşkuner, “Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi”, Ankara Univ Vet Fak Derg, c. 53, sy. 2, ss. 91–95, 2006, doi: 10.1501/Vetfak_0000000079.
ISNAD Yarım, Fatma Gül vd. “Şap hastalıklı Danalarda Plazma Monosit Kemoatraktan Protein-1 Ve İnterlökin-1α düzeylerinin Ve Bu düzeylerle Kan Lenfosit Ve Monosit sayıları arasındaki ilişkilerin Incelenmesi”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 53/2 (Haziran 2006), 91-95. https://doi.org/10.1501/Vetfak_0000000079.
JAMA Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A. Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Univ Vet Fak Derg. 2006;53:91–95.
MLA Yarım, Fatma Gül vd. “Şap hastalıklı Danalarda Plazma Monosit Kemoatraktan Protein-1 Ve İnterlökin-1α düzeylerinin Ve Bu düzeylerle Kan Lenfosit Ve Monosit sayıları arasındaki ilişkilerin Incelenmesi”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 53, sy. 2, 2006, ss. 91-95, doi:10.1501/Vetfak_0000000079.
Vancouver Yarım FG, Nisbet C, Öcal N, Çiftçi G, Coşkuner A. Şap hastalıklı danalarda plazma monosit kemoatraktan protein-1 ve İnterlökin-1α düzeylerinin ve bu düzeylerle kan lenfosit ve monosit sayıları arasındaki ilişkilerin incelenmesi. Ankara Univ Vet Fak Derg. 2006;53(2):91-5.