In this study, it was aimed to investigate the serum levels of ANGPTL4, FGF21, IL-1β, IL-6, SOD, MDA, and serum biochemical and hematological parameters in cows with subclinical ketosis. The mean serum β-hydroxybutyric acid (BHB) level was 1.37 ± 0.04 mmol/L in 10 dairy cows aged 3-5 years that were <21 days postpartum and diagnosed with subclinical ketosis. The mean serum BHB level was 0.40 ± 0.08 mmol/L in 10 healthy dairy cows in the same period and in the same age range. An increase in serum AST (P<0.001) and a decrease in serum albumin levels (P<0.05) indicated altered liver functions. An increase in serum non-esterified fatty acid (P<0.001) and decreases in serum HDL, triglyceride, and total cholesterol levels (P<0.05) were interpreted as indicators of increased metabolic pathology risk due to negative energy balance. Increases in serum ANGPTL4, FGF2, IL-1β, IL-6, and MDA (P<0.001) and SOD levels (P<0.05) were evaluated as indicators of the development of effective metabolic, inflammatory, and oxidative stress.
It was concluded that significant increases in serum ANGPTL4, FGF2, IL-1β, IL-6, and MDA and SOD levels in dairy cows with subclinical ketosis were associated with negative energy balance, effective cytokine responses, and oxidative stress.
Cytokines, dairy cows, energy-related biochemicals, hepatokines, Subclinical ketosis
Birincil Dil | İngilizce |
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Konular | Veteriner Hekimlik |
Bölüm | Araştırma Makalesi |
Yazarlar |
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Destekleyen Kurum | This study was supported by Ankara University Scientific Research Grant (grant no. 20B0239002). |
Proje Numarası | Grant no. 20B0239002 |
Teşekkür | This study is not produced from a doctoral-PhD or master’s thesis or presented at scientific meetings. |
Yayımlanma Tarihi | 30 Aralık 2022 |
Yayınlandığı Sayı | Yıl 2023Cilt: 70 Sayı: 1 |
Bibtex | @araştırma makalesi { auvfd907076, journal = {Ankara Üniversitesi Veteriner Fakültesi Dergisi}, issn = {1300-0861}, eissn = {1308-2817}, address = {}, publisher = {Ankara Üniversitesi}, year = {2023}, volume = {70}, number = {1}, pages = {37 - 42}, doi = {10.33988/auvfd.907076}, title = {Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis}, key = {cite}, author = {Kurtdede, Efe and Kurtdede, Arif and Öcal, Naci and Kara, Erdal} } |
APA | Kurtdede, E. , Kurtdede, A. , Öcal, N. & Kara, E. (2023). Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 70 (1) , 37-42 . DOI: 10.33988/auvfd.907076 |
MLA | Kurtdede, E. , Kurtdede, A. , Öcal, N. , Kara, E. "Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis" . Ankara Üniversitesi Veteriner Fakültesi Dergisi 70 (2023 ): 37-42 <http://vetjournal.ankara.edu.tr/tr/pub/issue/74067/907076> |
Chicago | Kurtdede, E. , Kurtdede, A. , Öcal, N. , Kara, E. "Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis". Ankara Üniversitesi Veteriner Fakültesi Dergisi 70 (2023 ): 37-42 |
RIS | TY - JOUR T1 - Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis AU - EfeKurtdede, ArifKurtdede, NaciÖcal, ErdalKara Y1 - 2023 PY - 2023 N1 - doi: 10.33988/auvfd.907076 DO - 10.33988/auvfd.907076 T2 - Ankara Üniversitesi Veteriner Fakültesi Dergisi JF - Journal JO - JOR SP - 37 EP - 42 VL - 70 IS - 1 SN - 1300-0861-1308-2817 M3 - doi: 10.33988/auvfd.907076 UR - https://doi.org/10.33988/auvfd.907076 Y2 - 2021 ER - |
EndNote | %0 Ankara Üniversitesi Veteriner Fakültesi Dergisi Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis %A Efe Kurtdede , Arif Kurtdede , Naci Öcal , Erdal Kara %T Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis %D 2023 %J Ankara Üniversitesi Veteriner Fakültesi Dergisi %P 1300-0861-1308-2817 %V 70 %N 1 %R doi: 10.33988/auvfd.907076 %U 10.33988/auvfd.907076 |
ISNAD | Kurtdede, Efe , Kurtdede, Arif , Öcal, Naci , Kara, Erdal . "Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis". Ankara Üniversitesi Veteriner Fakültesi Dergisi 70 / 1 (Aralık 2022): 37-42 . https://doi.org/10.33988/auvfd.907076 |
AMA | Kurtdede E. , Kurtdede A. , Öcal N. , Kara E. Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis. Ankara Univ Vet Fak Derg. 2023; 70(1): 37-42. |
Vancouver | Kurtdede E. , Kurtdede A. , Öcal N. , Kara E. Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2023; 70(1): 37-42. |
IEEE | E. Kurtdede , A. Kurtdede , N. Öcal ve E. Kara , "Serum ANGPTL4 and FGF2, energy-related blood biochemicals, cytokine responses and oxidative stress in dairy cows with subclinical ketosis", Ankara Üniversitesi Veteriner Fakültesi Dergisi, c. 70, sayı. 1, ss. 37-42, Ara. 2022, doi:10.33988/auvfd.907076 |