Letter to Editor
Detection of pathomorphological and immunohistochemical findings of tuberculosis in cattle slaughtered in Ankara and its surroundings
Abstract
Macroscopical and microscopical lesions were examined that 4-6 years old, different sex and breeds, 86 of cattle which detected tuberculosis from all materials were collected from slaughterhouses of Ankara and its surroundings. Generally 78 (91%) were located in the lungs, pleura and regional lymph nodes, 5 (6%) were located in the liver and portal lymph nodes, and 3 (3%) were generalised. Pathomorphologically, 81 (94%) comprised miliar-nodular tubercles, and 5 (6%) were determined to be chronic organ tuberculosis. Ziehl-Neelsen (ZN) stained sections revealed acide fast bacille (AFB) in lung, lymph nodes, liver and trachea (96%). Immunohistochemically, M. bovis antigens were seen in the macrophages, necrotic areas, and the Langhans giant cells (96%) in the same tissues but generally the number and intensity of the positivity were much higher than ZN
Keywords
References
- Anda JH, Evangelista R, Valencia GL, Hodgers MM (1997): An abattoir monitoring system for diagnosis of tuberculosis in cattle in Baja California, Mexico. J Am Vet Med Assoc, 211, 709-711.
- Anonymous (1991): TB and deer farming: Return of the king’s evil? Lancet, 338, 1243-1244.
- Atalay Vural S, Tunca R (2001): Generalized tuberculosis in a 45 day-old calf. Deutsc Tierrär Wochen, 108, 468-470.
- Beytut E (2001): Pathological examinations on the localization of lesions and incidence of tuberculosis in cattle in Kars city and its surrounding. Vet J Kafkas Uni, 7, 15-25.
- Cassidy JP, Bryson SD, Neill SD (1999): Tonsillar lesions in cattle naturally infected with Mycobacterium bovis. Vet Rec, 144, 139-142.
- Caswell JL, Williams KJ (2008): Respiratory system. Tuberculosis. 606-610. In: Maxie, MG (Ed), Jubb, Kennedy and Palmer’s Pathology of Domestic Animals, 5th ed. Elsevier, China.
- Corner LA, Melville L, McCubbin K (1990): Efficiency of inspection procedures for the detection of tuberculosis lesions in cattle. Aust Vet J, 67, 389-392.
- Delahay RJ, Leeuw ANS, Barlow AM, Clifton-Hadley RS, Cheeseman CL (2002): The status of Mycobacterium bovis infection in UK wild mammal: A review. Vet J, 164, 90-105.
- Deshpande BR, Sardeshpande PD, Sane CR (1966): Tuberculous endometritis in a buffalo cows. Indian Vet J, 43, 288-291.
- Diker F (1989): Bursa yöresinde cesitli ırk sigirlarda gorulen tuberkuloz lezyonlarinin organlara dagılısı ve histolojik yapilari. Pendik Hayv Hast Merk Araş Enst Derg, 20, 78-94.
- Duffield BJ, Norton JH, Streeten TA (1985): Application of the comparative cervical test to the identification of false positive reactions to the bovine tuberculin caudal fold test. Aust Vet J, 62, 424-426.
- Essey MA, Koller MA (1994): Status of bovine tuberculosis in North America. Vet Microbiol, 40, 15-22.
- Francis J (1958): Tuberculosis in Animals and Man. A Study in Comparative Pathology. Cassell and Company, London.
- Guilbrid PDL, Rollinson DHL, McAnulty EG, Alley JG, Wells EA (1963): Tuberculosis in the free living African (Cape) buffalo (Syncerus CafferCaffer Sparrman). J Comp Path, 73, 337-358.
- Gutierrez Cancela MM, Garcia Marin JF (1993): Comparison of Ziehl-Neelsen staining and immunohistochemistry for the detection of Mycobacterim bovis in bovine and caprine tuberculous lesions. J Comp Path, 109, 361-370.
- Jones TC, Hunt RD, King NW (1994): Diseases caused by bacteria. 413-504. In: Jones TC, Hunt RD, King NW (Eds), Veterinary Pathology, 6th ed. Williams and Wilkins, Baltimore.
- Lepper WD, Pearson CW (1973): The route of infection in tuberculosis in beef cattle. Aust Vet J, 49, 266-267.
- Lesslie IW, Birn KJ (1967): Tuberculosis in cattle caused by the avian type tubercle bacillus. Vet Rec, 80, 559-564.
- Lugton IW, Wobeser G, Morris RS, Caley P (1997): Epidemiology of Mycobacterium bovis infection in feral ferrets (Mustela furo) in New Zealand: I.Pathology and diagnosis. New Zealand Vet J, 45, 140-150.
- McKay WM (1959): A clinical study of bovine tuberculosis in Banffshire. The pathological lesions, part 2. British Vet J, 115, 370-377.
- McIlroy SG, Neill SD, McCracken RM (1986): Pulmonary lesion and Mycobacterium bovis excretion from the respiratory tract of tuberculin reacting cattle. Vet Rec, 118, 718-721.
- Murray PR (1993): Bacteriology. 1-27. In: Murray PR, Drew WL, Kobarashi GS, Thompson IH (Eds), Medical Microbiology. Wolfe Publishing, London.
- Ortatatli M, Ciftci MK, Tuzcu M (1998): Sığırlarda tüberküloz ve diğer granulomatöz pnömoniler üzerinde patolojik incelemeler. Selçuk Univ J Vet Sci, 14, 139-150.
- Ozmen O, Kurşun O, Ozcelik M (2005): Bovine tuberculosis in Burdur, southern Turkey: Epidemiological, pathological and economic study. Int J Tuberc Lung Dis, 9,1398-1402.
- Palmer MV, Waters WR, Whipple DL (2002): Lesion development in white-tailed deer (Odocoileu virginianus) experimentally infected with Mycobacterium bovis. Vet Pathol, 39, 334-340.
- Ragg JR, Waldrup KA, Moller H (1995): The distribution of gross lesions of tuberculosis caused by Mycobacterium bovis in feral ferrets (Mustela furo) from Otago, New Zealand. New Zealand Vet J, 43, 338-341.
- Roels S, Walravens K, Saegerman C, Thelissen M, Vanopdenbosch E, Godfroid J (2003): Mycobacterium bovis meningitis in a cow with clinical signs of BSE. Vet Rec, 152, 807-808.
- Stampt JT (1944): A review of the pathogenesis and pathology of bovine tuberculosis with special reference to practical problems. Vet Rec, 56, 443-446.
- Styblo K, Rouillon A (1981): Tuberculosis in the world estimated global incidence of smear positive pulmonary tuberculosis. Unreliability of officially reported figures on tuberculosis. Bull Int Uni Tuberc, 56, 118-126.
- Tammemagi L, Simmons GC, Kelman R, Hall WT (1973): A study of tuberculosis-like lesions in cattle slaughtred in Queensland meatworks. Aust Vet J, 49, 507- 511.
- Whipple DL, Bolin CA, Miller JM (1996): Distribution of lesions in cattle infected with Mycobacterium bovis. J Vet Diagn Invest, 8, 351-354.
- Whiting TL, Tessaro SV (1994): An abattoir study of tuberculosis in a herd of farmed elk. Canadian Vet J, 35, 497-501.
Ankara ve çevresinde bulunan mezbahalarda kesilen sığırlarda saptanan tüberkülozunpatomorfolojik ve immunohistokimyasal bulgularının incelenmesi
Abstract
Bu çalışmada Ankara ve çevre il/ilçe mezbahanelerinde kesilen 4-6 yaşlı, farklı ırk ve cinsiyette 86 tüberkülozlu sığırda saptanan makroskobik ve mikroskobik lezyonlar incelendi. Lezyonların 78’inin (%91) akciğer, plöra ve bölge lenf düğümlerinde, 5’inin (%6) karaciğer ve portal lenf düğümlerinde bulunduğu, 3’ünün (%3) ise generalize olduğu görüldü. Bunlardan, 81’i (%94) milier-nodüler tüberküller ve 5’i (%6) kronik organ tüberkülozu şeklindeydi. Bu hayvanların %96’sında akciğer, bölge lenf düğümleri, karaciğer ve traheadan yapılan Ziehl-Neelsen (ZN) boyamada aside dirençli basiller gözlendi. İmmunohistokimyasal olarak da olguların %96’sında aynı dokularda M. bovis antijenleri makrofajların sitoplazmasında, nekrotik alanlarda serbest halde ve Langhans dev hücrelerinde dikkati çekti. Her iki boyamada aynı oranda etken boyanması saptanmasına rağmen genel olarak immunohistokimyasal boyamalarda etken hem çok daha belirgindi hem de pozitiflik daha yoğundu
Keywords
References
- Anda JH, Evangelista R, Valencia GL, Hodgers MM (1997): An abattoir monitoring system for diagnosis of tuberculosis in cattle in Baja California, Mexico. J Am Vet Med Assoc, 211, 709-711.
- Anonymous (1991): TB and deer farming: Return of the king’s evil? Lancet, 338, 1243-1244.
- Atalay Vural S, Tunca R (2001): Generalized tuberculosis in a 45 day-old calf. Deutsc Tierrär Wochen, 108, 468-470.
- Beytut E (2001): Pathological examinations on the localization of lesions and incidence of tuberculosis in cattle in Kars city and its surrounding. Vet J Kafkas Uni, 7, 15-25.
- Cassidy JP, Bryson SD, Neill SD (1999): Tonsillar lesions in cattle naturally infected with Mycobacterium bovis. Vet Rec, 144, 139-142.
- Caswell JL, Williams KJ (2008): Respiratory system. Tuberculosis. 606-610. In: Maxie, MG (Ed), Jubb, Kennedy and Palmer’s Pathology of Domestic Animals, 5th ed. Elsevier, China.
- Corner LA, Melville L, McCubbin K (1990): Efficiency of inspection procedures for the detection of tuberculosis lesions in cattle. Aust Vet J, 67, 389-392.
- Delahay RJ, Leeuw ANS, Barlow AM, Clifton-Hadley RS, Cheeseman CL (2002): The status of Mycobacterium bovis infection in UK wild mammal: A review. Vet J, 164, 90-105.
- Deshpande BR, Sardeshpande PD, Sane CR (1966): Tuberculous endometritis in a buffalo cows. Indian Vet J, 43, 288-291.
- Diker F (1989): Bursa yöresinde cesitli ırk sigirlarda gorulen tuberkuloz lezyonlarinin organlara dagılısı ve histolojik yapilari. Pendik Hayv Hast Merk Araş Enst Derg, 20, 78-94.
- Duffield BJ, Norton JH, Streeten TA (1985): Application of the comparative cervical test to the identification of false positive reactions to the bovine tuberculin caudal fold test. Aust Vet J, 62, 424-426.
- Essey MA, Koller MA (1994): Status of bovine tuberculosis in North America. Vet Microbiol, 40, 15-22.
- Francis J (1958): Tuberculosis in Animals and Man. A Study in Comparative Pathology. Cassell and Company, London.
- Guilbrid PDL, Rollinson DHL, McAnulty EG, Alley JG, Wells EA (1963): Tuberculosis in the free living African (Cape) buffalo (Syncerus CafferCaffer Sparrman). J Comp Path, 73, 337-358.
- Gutierrez Cancela MM, Garcia Marin JF (1993): Comparison of Ziehl-Neelsen staining and immunohistochemistry for the detection of Mycobacterim bovis in bovine and caprine tuberculous lesions. J Comp Path, 109, 361-370.
- Jones TC, Hunt RD, King NW (1994): Diseases caused by bacteria. 413-504. In: Jones TC, Hunt RD, King NW (Eds), Veterinary Pathology, 6th ed. Williams and Wilkins, Baltimore.
- Lepper WD, Pearson CW (1973): The route of infection in tuberculosis in beef cattle. Aust Vet J, 49, 266-267.
- Lesslie IW, Birn KJ (1967): Tuberculosis in cattle caused by the avian type tubercle bacillus. Vet Rec, 80, 559-564.
- Lugton IW, Wobeser G, Morris RS, Caley P (1997): Epidemiology of Mycobacterium bovis infection in feral ferrets (Mustela furo) in New Zealand: I.Pathology and diagnosis. New Zealand Vet J, 45, 140-150.
- McKay WM (1959): A clinical study of bovine tuberculosis in Banffshire. The pathological lesions, part 2. British Vet J, 115, 370-377.
- McIlroy SG, Neill SD, McCracken RM (1986): Pulmonary lesion and Mycobacterium bovis excretion from the respiratory tract of tuberculin reacting cattle. Vet Rec, 118, 718-721.
- Murray PR (1993): Bacteriology. 1-27. In: Murray PR, Drew WL, Kobarashi GS, Thompson IH (Eds), Medical Microbiology. Wolfe Publishing, London.
- Ortatatli M, Ciftci MK, Tuzcu M (1998): Sığırlarda tüberküloz ve diğer granulomatöz pnömoniler üzerinde patolojik incelemeler. Selçuk Univ J Vet Sci, 14, 139-150.
- Ozmen O, Kurşun O, Ozcelik M (2005): Bovine tuberculosis in Burdur, southern Turkey: Epidemiological, pathological and economic study. Int J Tuberc Lung Dis, 9,1398-1402.
- Palmer MV, Waters WR, Whipple DL (2002): Lesion development in white-tailed deer (Odocoileu virginianus) experimentally infected with Mycobacterium bovis. Vet Pathol, 39, 334-340.
- Ragg JR, Waldrup KA, Moller H (1995): The distribution of gross lesions of tuberculosis caused by Mycobacterium bovis in feral ferrets (Mustela furo) from Otago, New Zealand. New Zealand Vet J, 43, 338-341.
- Roels S, Walravens K, Saegerman C, Thelissen M, Vanopdenbosch E, Godfroid J (2003): Mycobacterium bovis meningitis in a cow with clinical signs of BSE. Vet Rec, 152, 807-808.
- Stampt JT (1944): A review of the pathogenesis and pathology of bovine tuberculosis with special reference to practical problems. Vet Rec, 56, 443-446.
- Styblo K, Rouillon A (1981): Tuberculosis in the world estimated global incidence of smear positive pulmonary tuberculosis. Unreliability of officially reported figures on tuberculosis. Bull Int Uni Tuberc, 56, 118-126.
- Tammemagi L, Simmons GC, Kelman R, Hall WT (1973): A study of tuberculosis-like lesions in cattle slaughtred in Queensland meatworks. Aust Vet J, 49, 507- 511.
- Whipple DL, Bolin CA, Miller JM (1996): Distribution of lesions in cattle infected with Mycobacterium bovis. J Vet Diagn Invest, 8, 351-354.
- Whiting TL, Tessaro SV (1994): An abattoir study of tuberculosis in a herd of farmed elk. Canadian Vet J, 35, 497-501.
There are 32 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Surgery |
| Other ID | JA88AS22CP |
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 1, 2010 |
| Published in Issue | Year 2010Volume: 57 Issue: 4 |